Linda C. Cendales et al
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Abstract
As more data becomes available, the Banff 2007 working classification of skin-containing vascularized composite allograft (VCA) pathology is expected to evolve and develop. This report represents the Banff VCA Working Group's consensus on the first revision of the 2007 scoring system. Prior to the 2022 Banff-CST Joint Meeting, eighty-three clinicians and/or researchers were invited to a virtual meeting to discuss whether the 2007 Banff VCA system called for a revision. Unanimously, it was determined that the vascular changes were to be included in the first revision. Subsequently, two international online surveys, each followed by virtual discussions, were launched. The goals were: (1) to identify which changes define severe rejection, (2) to grade their importance in the evaluation of severe rejection, (3) to identify emerging criteria to diagnose rejection. A final hybrid (in person and virtual) discussion at the BANFF/CST join meeting finalized the terminology, the definition, a scoring system, and a reporting system of the vascular changes. This proposal represents an international consensus on this topic and establishes the first revision of the Banff 2007 working classification of skin-containing vascularized composite allograft pathology.
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The comment period will be open until June 30, 2023. All comments will be reviewed and considered by the Banff meeting report author groups prior to finalizing the manuscripts and submission for formal peer review.
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